Atrial fibrillation (AF) has been linked to cerebral small vessel disease (CSVD). This study examined the sex-specific differences in CSVD between patients with and without AF and the implications for cognitive and physical performance.
This study examines the relationship between witnessing parental violence—a specific type of adverse childhood experiences (ACEs)—and frailty in adulthood, employing a graded exposure measurement approach.
Hospital discharge to a long-term care facility (LTCF) often represents an opportunity to reassess care goals, treatment intensity, and medication use. We examined changes in glucose-lowering medication (GLM) dispensing following first hospital discharge to LTCFs and whether these changes differed by resid...
Although daily-life gait speed (DGS) may better reflect real-world walking than laboratory- or clinic-based gait speed (LGS), it is unclear whether DGS provides superior discriminatory value for clinical outcomes. We compared LGS and DGS on their discriminative abilities concerning the risk of prefrailty/f...
To provide insight into the point prevalence of bacteriuria in frail older adults residing in Dutch nursing homes (NHs), to describe identified bacteria, and to investigate possible associations between resident characteristics and asymptomatic bacteriuria (ASB).
Despite the widespread usage of the Short Physical Performance Battery (SPPB), psychometric limitations in the SPPB have impeded its use for outcome monitoring and clinical decision making. We propose an alternative assessment and scoring approach for the SPPB, and we compared the modified and the original...
To describe the 5-year functional and cognitive outcomes of older adults undergoing coronary artery bypass grafting (CABG) ± valve surgery, and to identify preoperative factors associated with poor recovery.
To investigate perceived physical fatigability (PPF) as a novel predictor of cognitive frailty (CF) and elucidate mediating roles of physical capability markers in community-dwelling older adults.
This study aimed to analyze the associations of the Phenotypic Aging Index (PAI) with health outcomes, functional outcomes, and health care utilization using UK Biobank data. Specifically, we assessed whether the PAI predicts these outcomes after adjusting for polygenic risk scores (PRS) and demographic an...