This study aimed to analyze the associations of the Phenotypic Aging Index (PAI) with health outcomes, functional outcomes, and health care utilization using UK Biobank data. Specifically, we assessed whether the PAI predicts these outcomes after adjusting for polygenic risk scores (PRS) and demographic an...
Dietary intake is a crucial factor for healthy longevity. This study examined the association between meal-skipping habits in early and midlife and physical frailty in later life among community-dwelling older adults.
The objective of this analysis was to describe the association of dysphagia and frailty in persons living with dementia (PLWD) residing in skilled nursing facilities (SNFs) who experienced hospitalization.
The goal of this study was to investigate the associations between the frailty index (FI) and allostatic load (AL) to determine if allostatic load contains “key” biomarkers of frailty. If so, AL may offer a more concise health measure using only routine, administrative data.
To develop and validate a machine learning–based risk score—the Acute Care for Elders (ACE) Risk Score—that integrates the Clinical Frailty Scale (CFS) with readily available clinical and laboratory data to predict adverse outcomes in older hospitalized patients.
This study investigates the relationship between frailty status and white matter integrity (WMI) in older adults, focusing on associations with frailty status.
Delirium is a common complication in older patients hospitalized with COVID-19 and is associated with short-term functional and cognitive decline. This study evaluated whether in-hospital delirium is associated with long-term mortality and changes in frailty and cognition.
Important risk factors for mortality include frailty and illness severity. The National Early Warning Score 2 (NEWS2) is widely used to assess acute illness severity and mortality risk, but age and frailty's impact on the association between NEWS2 and mortality is less understood, particularly in nonh...
People with HIV (PWH) likely need short-term skilled nursing facility (SNF) care more than people with greater financial and social support to remain home. Therefore, we sought to understand how frailty among health profiles with distinct driving conditions, antiretroviral therapy (ART), and sociodemograph...
Frailty and poor psychological functioning remain major aging-related public and clinical health challenges. The multidimensional nature of these constructs, along with diverse assessment methods, complicate the study of their relationship. This study aims to examine the cross-sectional and longitudinal re...