JAMDA
December 17, 2014
Showing 131 - 140 of 141 results
JAMDA
December 15, 2014
A Double-Blind Randomized Placebo-Controlled Withdrawal Trial Comparing Memantine and Antipsychotics for the Long-Term Treatment of Function and Neuropsychiatric Symptoms in People With Alzheimer's Disease (MAIN-AD)
Neuropsychiatric symptoms in Alzheimer disease (AD) cause significant distress and present a complex clinical challenge for treatment. Pharmacological treatment options are limited to antipsychotics, which carry extensive safety issues. There is emerging evidence to support the potential benefits of memant...
JAMDA
October 23, 2014
The Study of Mental and Resistance Training (SMART) Study—Resistance Training and/or Cognitive Training in Mild Cognitive Impairment: A Randomized, Double-Blind, Double-Sham Controlled Trial
Mild cognitive impairment (MCI) increases dementia risk with no pharmacologic treatment available.
JAMDA
October 10, 2014
Role of the Extended Haplotype in the Worsening of Psychotic Symptoms and Treatment Response in Alzheimer DiseaseMAPTRole of the Extended Haplotype in the Worsening of Psychotic Symptoms and Treatment Response in Alzheimer Disease
There is evidence that neurofibrillary tangle (NFT) burden is associated with psychotic symptoms in Alzheimer disease (AD). However, it is not clear whether this association is direct or mediated through the increased cognitive impairment associated with NFTs.
JAMDA
July 14, 2014
Risk of Dementia Among Patients With Asthma: A Nationwide Longitudinal Study
Previous studies have suggested an association between asthma and dementia, but the results are still inconsistent.
JAMDA
June 19, 2014
Cognitive Deficit Reversal as Shown by Changes in the Veterans Affairs Saint Louis University Mental Status (SLUMS) Examination Scores 7.5 Years Later
The Veterans Affairs Saint Louis University Mental Status (SLUMS) examination is a screening tool that has the sensitivity to detect mild neurocognitive impairment and dementia. This study explores patients' cognitive impairment trajectories based on the SLUMS examination score changes after 7.5 years...
JAMDA
April 7, 2014
Body-Mass Index and Mortality in Incident Dementia: A Cohort Study on 11,398 Patients From SveDem, the Swedish Dementia Registry
Body mass index (BMI) is used worldwide as an indirect measure of nutritional status and has been shown to be associated with mortality. Controversy exists over the cut points associated with lowest mortality, particularly in older populations. In patients suffering from dementia, information on BMI and mo...
JAMDA
March 13, 2014
Psychotropic Drugs in Patients With Alzheimer's Disease: A Longitudinal Study by the Registry of Dementias of Girona (ReDeGi) in Catalonia, Spain
Psychotropic drugs are usually prescribed to deal with behavioral and psychological symptoms of dementia, especially when nonpharmacologic approaches are not available or have limited efficacy. Poor outcomes and serious adverse events of the drugs used must be addressed, and risk-benefit ratios need to be ...
JAMDA
February 15, 2014
Transcranial Doppler to Measure Cerebral Blood Flow in Delirium Superimposed on Dementia. A Cohort Study
Delirium superimposed on dementia (DSD) is frequently not diagnosed, at great cost. Both delirium and dementia are associated with cerebral hypoperfusion. A switch to anaerobic glycolysis in the central nervous system during delirium compared to Alzheimer's dementia (AD) suggests greater hypoperfusion...
JAMDA
February 10, 2014
Effects of Dementia on Postoperative Outcomes of Older Adults With Hip Fractures: A Population-Based Study
To evaluate the association between dementia and postoperative outcomes of older adults with hip fractures.
