Atrial fibrillation (AF) has been linked to cerebral small vessel disease (CSVD). This study examined the sex-specific differences in CSVD between patients with and without AF and the implications for cognitive and physical performance.
This study examines the relationship between witnessing parental violence—a specific type of adverse childhood experiences (ACEs)—and frailty in adulthood, employing a graded exposure measurement approach.
In preventing atherosclerotic cardiovascular diseases (ASCVDs) in frail older people, it is essential to balance estimated cardiovascular disease (CVD) risk with potential treatment benefits and harms. Systematic Coronary Risk Evaluation 2-Older Persons (SCORE2-OP) estimates CVD risk in older people but ha...
Periodontal disease (PD), a prevalent condition in older adults, may impair nutritional status through reduced masticatory function, systemic inflammation, and altered dietary intake. However, few studies have examined the relationship between clinically assessed PD and validated nutritional risk metrics, ...
Hospital discharge to a long-term care facility (LTCF) often represents an opportunity to reassess care goals, treatment intensity, and medication use. We examined changes in glucose-lowering medication (GLM) dispensing following first hospital discharge to LTCFs and whether these changes differed by resid...
Frailty is a common geriatric syndrome associated with adverse health outcomes. Although gait speed is widely recognized as a predictor of frailty, the contribution of other gait parameters remains unclear, particularly among initially robust older adults. This study aimed to examine the associations betwe...
Although daily-life gait speed (DGS) may better reflect real-world walking than laboratory- or clinic-based gait speed (LGS), it is unclear whether DGS provides superior discriminatory value for clinical outcomes. We compared LGS and DGS on their discriminative abilities concerning the risk of prefrailty/f...
To provide insight into the point prevalence of bacteriuria in frail older adults residing in Dutch nursing homes (NHs), to describe identified bacteria, and to investigate possible associations between resident characteristics and asymptomatic bacteriuria (ASB).
Despite the widespread usage of the Short Physical Performance Battery (SPPB), psychometric limitations in the SPPB have impeded its use for outcome monitoring and clinical decision making. We propose an alternative assessment and scoring approach for the SPPB, and we compared the modified and the original...