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Showing 121 - 130 of 132 results

JAMDA

February 14, 2015

The Course of Neuropsychiatric Symptoms in Dementia: A 3-Year Longitudinal Study

Patients with dementia experience a wide range of neuropsychiatric symptoms. These symptoms often cause considerable distress to patients and caregivers, and often contribute to institutionalization. The current study examined the prevalence and course of neuropsychiatric symptoms in a large sample of pati...
JAMDA

December 17, 2014

SAIDO Learning as a Cognitive Intervention for Dementia Care: A Preliminary Study

The purpose of this study was to examine the beneficial effects on cognitive function by a cognitive intervention program designed for dementia care called Learning Therapy in Japan and SAIDO Learning in the United States (hereinafter “SAIDO Learning,” as appropriate). SAIDO Learning is a working memory tr...
JAMDA

December 15, 2014

A Double-Blind Randomized Placebo-Controlled Withdrawal Trial Comparing Memantine and Antipsychotics for the Long-Term Treatment of Function and Neuropsychiatric Symptoms in People With Alzheimer's Disease (MAIN-AD)

Neuropsychiatric symptoms in Alzheimer disease (AD) cause significant distress and present a complex clinical challenge for treatment. Pharmacological treatment options are limited to antipsychotics, which carry extensive safety issues. There is emerging evidence to support the potential benefits of memant...
JAMDA

October 10, 2014

Role of the Extended Haplotype in the Worsening of Psychotic Symptoms and Treatment Response in Alzheimer DiseaseMAPTRole of the Extended Haplotype in the Worsening of Psychotic Symptoms and Treatment Response in Alzheimer Disease

There is evidence that neurofibrillary tangle (NFT) burden is associated with psychotic symptoms in Alzheimer disease (AD). However, it is not clear whether this association is direct or mediated through the increased cognitive impairment associated with NFTs.