Showing 3391 - 3400 of 4930 results

JAMDA

June 28, 2018

Telomere Length and Frailty: The Helsinki Birth Cohort Study

Telomere length is associated with aging-related pathologies. Although the association between telomere length and frailty has been studied previously, only a few studies assessing longitudinal changes in telomere length and frailty exist.
JAMDA

June 22, 2018

Orthostatic Hypotension in the Elderly: A Marker of Clinical Frailty?

Orthostatic hypotension (OH) has high prevalence in frail older adults. However, its effect on mortality, disability, and hospitalization in frail older adults is poorly investigated. Thus, we assessed the relationship between the prevalence of OH and its effect on mortality, disability, and hospitalizatio...
JAMDA

June 22, 2018

Antipsychotic Deprescription for Older Adults in Long-term Care: The HALT Study

Despite limited efficacy and significant safety concerns, antipsychotic medications are frequently used to treat behavioral and psychological symptoms of dementia (BPSD) in long-term residential care. This study evaluates the sustained reduction of antipsychotic use for BPSD through a deprescribing interve...
JAMDA

June 20, 2018

Handgrip Strength Cannot Be Assumed a Proxy for Overall Muscle Strength

Dynapenia, low muscle strength, is predictive for negative health outcomes and is usually expressed as handgrip strength (HGS). Whether HGS can be a proxy for overall muscle strength and whether this depends on age and health status is controversial. This study assessed the agreement between HGS and knee e...